PUPPS is the most common skin condition in pregnancy and stands for pruritic urticarial papules and plaques of pregnancy. This shows up as a rash that is bumpy and itchy. It usually first appears in stretch marks on your belly, it can spread on your stomach to your arms, thighs, butt, but this doesn’t show up on your navel or your face. PUPPS affects about 1 in every 160 pregnancies and is most common in the third trimester among first-time moms and moms carrying multiples. While there are no known risks to you or your baby, the rash can be very itchy and bothersome. Topical corticosteroids and oral antihistamines are frequently prescribed to alleviate the itching. Hear the theories on what causes PUPPS, the evidence behind the medicines used to treat PUPPS, plus some natural remedies that may help you find some relief.