A fever is part of your body’s immune response as a natural defense to infection. The risks and benefits of fever during pregnancy are different than those of someone who is not pregnant. Running a fever during your pregnancy can be scary. Studies have linked maternal fevers to complications like autism, neural tube defects, oral clefts, and congenital heart defects. The best way to alleviate any fears or unknowns is to educate yourself about what temperature constitutes a fever, when to call your doctor or midwife, and what to do if you get a fever during your pregnancy. It is common to take over-the-counter medicine to reduce a fever. Over the years, attitudes towards the use of medications like acetaminophen have evolved. While doctors have long considered this safe, more recent research raises questions about taking this over-the-counter medication during pregnancy.